Association between the DRB1*08032 histocompatibility antigen and methimazole-induced agranulocytosis in Japanese patients with Graves disease.

@article{Tamai1996AssociationBT,
  title={Association between the DRB1*08032 histocompatibility antigen and methimazole-induced agranulocytosis in Japanese patients with Graves disease.},
  author={Hironao Tamai and Tetsuo Sudo and Akinori Kimura and Toshio Mukuta and Sunao Matsubayashi and K. P. Kiran Kuma and Shigenobu Nagataki and Takehiko Sasazuki},
  journal={Annals of internal medicine},
  year={1996},
  volume={124 5},
  pages={
          490-4
        }
}
Objective: To determine the association between HLA class II genes and methimazole-induced agranulocytosis in patients with Graves disease. Design: Case-control study. Setting: Kuma Hospital, which specializes in thyroid diseases, in Kobe, Japan. Subjects: 24 patients with Graves disease who had methimazole-induced agranulocytosis diagnosed by peripheral granulocyte counts of less than 0.5 109/L, and 68 patients with Graves disease treated with methimazole, who were free from agranulocytosis… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 14 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 44 REFERENCES

Nomenclature for factors of the HLA system, 1995.

  • European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics
  • 1995

Resistance to autoimmune thyroid disease is associated with HLA-DQ.

  • The Journal of clinical endocrinology and metabolism
  • 1994
VIEW 1 EXCERPT

Similar Papers

Loading similar papers…