Association between the AUC0-24/MIC Ratio of Vancomycin and Its Clinical Effectiveness: A Systematic Review and Meta-Analysis

@inproceedings{Men2016AssociationBT,
  title={Association between the AUC0-24/MIC Ratio of Vancomycin and Its Clinical Effectiveness: A Systematic Review and Meta-Analysis},
  author={Peng Men and Hui-bo Li and Suo-di Zhai and Rong-Sheng Zhao and Nagendra R Hegde},
  booktitle={PloS one},
  year={2016}
}
BACKGROUND A target AUC0-24/MIC ratio of 400 has been associated with its clinical success when treating Staphylococcus aureus infections but is not currently supported by state-of-the-art evidence-based research. OBJECTIVE This current systematic review aimed to evaluate the available evidence for the association between the AUC0-24/MIC ratio of vancomycin and its clinical effectiveness on hospitalized patients and to confirm the existing target value of 400. METHODS PubMed, Embase, Web of… CONTINUE READING

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