Association between the -2518G/A polymorphism in the monocyte chemoattractant protein-1 (MCP-1) gene and myocardial infarction in Tunisian patients.

@article{Jemaa2008AssociationBT,
  title={Association between the -2518G/A polymorphism in the monocyte chemoattractant protein-1 (MCP-1) gene and myocardial infarction in Tunisian patients.},
  author={Riadh Jemaa and Hajer Rojbani and Amani Kallel and Samir Ben Ali and Moncef Feki and Sonia Chabrak and Monia Elasmi and Samah Haj Taieb and Ha{\"i}fa Sanhaji and Omar Souheil and Rachid Mechm{\`e}che and Naziha Kaabachi},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  year={2008},
  volume={390 1-2},
  pages={122-5}
}
BACKGROUND Monocyte chemoattractant protein-1 (MCP-1; gene name CCL2) has been suggested to play an important role in the initiation of atherosclerosis by recruiting monocytes to sites of injured endothelium. Recently, single nucleotide polymorphisms (SNPs) in the MCP-1 regulatory region have been identified. Controversial results regarding the association of the -2518G/A polymorphism of the MCP-1 gene with coronary artery disease (CAD) have been reported. In the present study, we examined a… CONTINUE READING

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