Association between telomere length in blood and mortality in people aged 60 years or older

  title={Association between telomere length in blood and mortality in people aged 60 years or older},
  author={R. Cawthon and K. Smith and E. O’Brien and Anna J. Sivatchenko and Richard A. Kerber},
  journal={The Lancet},
  • R. Cawthon, K. Smith, +2 authors Richard A. Kerber
  • Published 2003
  • Medicine
  • The Lancet
  • During normal ageing, the gradual loss of telomeric DNA in dividing somatic cells can contribute to replicative senescence, apoptosis, or neoplastic transformation. In the genetic disorder dyskeratosis congenita, telomere shortening is accelerated, and patients have premature onset of many age-related diseases and early death. We aimed to assess an association between telomere length and mortality in 143 normal unrelated individuals over the age of 60 years. Those with shorter telomeres in… CONTINUE READING
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