Association between telomere length and BCL2 gene rearrangements in low- and high-grade non-Hodgkin lymphomas.

@article{Cottliar2006AssociationBT,
  title={Association between telomere length and BCL2 gene rearrangements in low- and high-grade non-Hodgkin lymphomas.},
  author={Alejandra Silvina Hayde{\'e} Cottliar and Maria Noriega and Marina In{\'e}s Narbaitz and Andrea V. Rodriguez and Irma Rosa Slavutsky},
  journal={Cancer genetics and cytogenetics},
  year={2006},
  volume={171 1},
  pages={1-8}
}
Telomere length based on terminal restriction fragment (TRF) assay was evaluated in cells of bone marrow, lymph node, or both from 53 non-Hodgkin lymphoma (NHL) patients: 44 with follicular lymphoma (FL) and 9 with secondary diffuse large B-cell lymphoma (S-DLBCL) to FL. The TRF data were correlated with BCL2 gene rearrangement evaluated by nested and long-distance polymerase chain reaction approaches. Peripheral blood cells from 12 healthy donors were studied as controls. Both groups of NHL… CONTINUE READING

Similar Papers

Loading similar papers…