Association between stool enteropathogen quantity and disease in Tanzanian children using TaqMan array cards: a nested case-control study.

@article{PlattsMills2014AssociationBS,
  title={Association between stool enteropathogen quantity and disease in Tanzanian children using TaqMan array cards: a nested case-control study.},
  author={James A Platts-Mills and J. Michael Gratz and Esto Mduma and Erling Svensen and Caroline Amour and Jie Liu and Athanasia Maro and Queen Saidi and Ndealilia S Swai and Happiness H Kumburu and Benjamin Joseph James McCormick and Gibson Sammy Kibiki and Eric R Houpt},
  journal={The American journal of tropical medicine and hygiene},
  year={2014},
  volume={90 1},
  pages={133-8}
}
Etiologic studies of diarrhea are limited by uneven diagnostic methods and frequent asymptomatic detection of enteropathogens. Polymerase chain reaction-based stool pathogen quantification may help distinguish clinically significant infections. We performed a nested case-control study of diarrhea in infants from a community-based birth cohort in Tanzania. We tested 71 diarrheal samples and pre-diarrheal matched controls with a laboratory-developed TaqMan Array Card for 19 enteropathogens. With… CONTINUE READING
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