Association between some endocrine-disrupting chemicals and childhood obesity in biological samples of young girls: a cross-sectional study.

@article{Choi2014AssociationBS,
  title={Association between some endocrine-disrupting chemicals and childhood obesity in biological samples of young girls: a cross-sectional study.},
  author={Jaeyeon Choi and Jinhee Eom and Jiye Kim and Sanghouck Lee and Yunje Kim},
  journal={Environmental toxicology and pharmacology},
  year={2014},
  volume={38 1},
  pages={
          51-7
        }
}

Tables from this paper

Association of Endocrine Disrupting Chemicals, Bisphenol A and Phthalates, with Childhood Obesity: A Systematic Review
TLDR
The effects of BPA and phthalates have diverse mechanisms; these chemicals disrupt some functional, structural, and epigenetic mechanisms that control energy homeostasis, appetite regulation, lipid metabolism, and adipogenesis; however, additional longitudinal studies are needed to confirm and validate the current findings.
The Association between Bisphenol A Exposure and Obesity in Children—A Systematic Review with Meta-Analysis
TLDR
It was shown that BPA exposure itself increased the risk of obesity in children and that the relatively high-exposed group had a significantly higher risk of childhood obesity than the relatively low-exp exposed group.
Urinary Phthalate Levels in Relation to Obesity among a Sample of Egyptian Children
TLDR
An association between phthalates exposure and childhood and adolescent adiposity is suggested and physical indicators of obesity as body weight, BMI, WC, and HC were significantly positively correlated with urinary levels of MEHP and MEP, while urinary MBzP demonstrated a significant positive association with serum triglycerides levels.
Exposure to endocrine-disrupting chemicals and anthropometric measures of obesity: a systematic review and meta-analysis
TLDR
Most observational studies supported a positive association between obesity and exposure to EDCs, and underscore the need to limit human exposure toEDCs in light of the evidence from animal and cell-based studies indicating the effects of these chemicals on adiposity.
Developmental Exposure to Environmental Chemicals and Metabolic Changes in Children.
Obesity and endocrine-disrupting chemicals
TLDR
The environmental obesogen model holds that exposure to obesogens elicits a predisposition to obesity and that such exposures may be an important yet overlooked factor in the obesity pandemic.
Is bisphenol A an environmental obesogen?
TLDR
Blood analysis and in vitro data clearly demonstrate that BPA promotes adipogenesis, lipid and glucose dysregulation, and adipose tissue inflammation, thus contributing to the pathophysiology of obesity.
Environmental exposure to urinary Bisphenol-A in North Indian children aged between 6 and 16 years and its association with body mass index
TLDR
The study investigates the effect of environmental risk factors among North Indian children aged between 6 and 16 years associated with body mass index by comparing fasting and non-fasting urine Bisphenol-A, urine creatinine, and serum thyroid levels with other potential confounding factors and recommends awareness programs and policy guidelines to reduce the potential exposure to other chemical migrations sources.
...
...

References

SHOWING 1-10 OF 27 REFERENCES
Association of endocrine disruptors and obesity: perspectives from epidemiological studies.
TLDR
This exploratory analysis found several associations between phthalate metabolites and obesity, including notable differences by gender, but the cross-sectional data are a limitation.
Association between bisphenol A exposure and body mass index in Chinese school children: a cross-sectional study
TLDR
Investigation of the association between BPA exposure and body mass index (BMI) in school children in China showed that urine BPA concentrations were significantly associated with increasing BMI values in all subjects after adjustment for age and sex and the results were similar before and after corrected by urine specific gravity.
Endocrine‐disrupting chemicals and obesity development in humans: A review
TLDR
The study findings suggest that some endocrine disruptors may play a role for the development of the obesity epidemic, in addition to the more commonly perceived putative contributors.
Association between urinary bisphenol A concentration and obesity prevalence in children and adolescents.
TLDR
Urinary BPA concentration was significantly associated with obesity in this cross-sectional study of children and adolescents and could not rule out the possibility that obese children ingest food with higher BPA content or have greater adipose stores of BPA.
Positive relationship between androgen and the endocrine disruptor, bisphenol A, in normal women and women with ovarian dysfunction.
TLDR
There is a strong relationship between serum BPA and androgen concentrations, speculatively due to the effect of androgen on the metabolism of BPA, in women with ovarian dysfunction and obesity.
Urinary Bisphenol A Levels and Measures of Obesity: Results from the National Health and Nutrition Examination Survey 2003–2008
TLDR
A positive association between increasing levels of urinary BPA and both measures of obesity, independent of potential confounding factors including, smoking, alcohol consumption, and serum cholesterol levels is observed.
Association of urinary phthalate metabolite concentrations with body mass index and waist circumference: a cross-sectional study of NHANES data, 1999–2002
BackgroundAlthough diet and activity are key factors in the obesity epidemic, laboratory studies suggest that endocrine disrupting chemicals may also affect obesity.MethodsWe analyzed associations
Daily Bisphenol A Excretion and Associations with Sex Hormone Concentrations: Results from the InCHIANTI Adult Population Study
TLDR
Higher daily BPA excretion was associated with higher total testosterone concentrations in men, in models adjusted for age and study site, and in models additionally adjusted for smoking, measures of obesity, and urinary creatinine concentrations.
The Endocrine Disruptor 4-Nonylphenol Promotes Adipocyte Differentiation and Induces Obesity in Mice
TLDR
4-NP may be expected to increase the incidence of obesity and can act as a potential chemical stressor for obesity and obesity-related disorders.
...
...