Association between serum uric acid and inflammation in rheumatoid arthritis: perspective on lowering serum uric acid of leflunomide.

@article{Choe2015AssociationBS,
  title={Association between serum uric acid and inflammation in rheumatoid arthritis: perspective on lowering serum uric acid of leflunomide.},
  author={J. Choe and Seong Kyu Kim},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  year={2015},
  volume={438},
  pages={29-34}
}
BACKGROUND The association between serum uric acid concentrations and inflammation in patients with rheumatoid arthritis (RA) has been still controversial. METHODS A total of 172 patients with RA who added leflunomide to methotrexate (MTX) in their treatment regimens were enrolled in this study. Twenty-seven RA patients taking MTX without leflunomide were also recruited in order to assess the fractional excretion of uric acid (FEUA). RESULTS After leflunomide therapy for an average of 4… CONTINUE READING