Association between schizophrenia and common variation in neurocan (<ce:italic>NCAN</ce:italic>), a genetic risk factor for bipolar disorder

  title={Association between schizophrenia and common variation in neurocan (<ce:italic>NCAN</ce:italic>), a genetic risk factor for bipolar disorder},
  author={Thomas W. M{\"u}hleisen and Manuel Mattheisen and Jana Strohmaier and Franziska Degenhardt and Sven Cichon},
  journal={Schizophrenia Research},
A recent study found genome-wide significant association between common variation in the gene neurocan (NCAN, rs1064395) and bipolar disorder (BD). In view of accumulating evidence that BD and schizophrenia partly share genetic risk factors, we tested this single-nucleotide polymorphism for association with schizophrenia in three independent patient-control samples of European ancestry, totaling 5061 patients and 9655 controls. The rs1064395 A-allele, which confers risk for BD, was… CONTINUE READING
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