Association between polymorphisms at N-acetyltransferase 1 (NAT1) & risk of oral leukoplakia & cancer

@inproceedings{Majumder2012AssociationBP,
  title={Association between polymorphisms at N-acetyltransferase 1 (NAT1) & risk of oral leukoplakia & cancer},
  author={Mousumi Majumder and Saurabh Ghosh and Bidyut Kumar Roy},
  booktitle={The Indian journal of medical research},
  year={2012}
}
BACKGROUND & OBJECTIVES N-acetyltransferases 1 and 2 (NAT1 and NAT2) are important enzymes for metabolism of tobacco carcinogens. Due to polymorphisms, improper activities of these enzymes might lead to the formation of DNA adducts that may modulate risk of tobacco related oral precancer and cancer. Previously, it was shown that NAT2 polymorphisms did not modulate the risk of oral precancer and cancer. We undertook this study to check whether polymorphisms at NAT1 can modulate the risk of oral… CONTINUE READING

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