Association between polymorphism of the dopamine transporter gene and early smoking onset: an interaction risk on nicotine dependence

@article{Ling2004AssociationBP,
  title={Association between polymorphism of the dopamine transporter gene and early smoking onset: an interaction risk on nicotine dependence},
  author={Daijun Ling and Tianhua Niu and Yan Feng and Houxun Xing and Xiping Xu},
  journal={Journal of Human Genetics},
  year={2004},
  volume={49},
  pages={35-39}
}
AbstractPrevious studies suggested that a polymorphism in the dopamine transporter gene (SLC6A3) is associated with nicotine dependence and age of smoking onset, but the conclusion was controversial. To detect the association of a G → A polymorphism (NCBI dbSNP cluster ID: rs27072) in 3′-untranslated region of the SLC6A3 with nicotine dependence and early smoking onset, we recruited 253 sibships including 668 nicotine-dependent siblings from a rural district of China. The sibship disequilibrium… CONTINUE READING

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