Association between pharmacokinetics of adalimumab and mucosal healing in patients with inflammatory bowel diseases.

@article{Roblin2014AssociationBP,
  title={Association between pharmacokinetics of adalimumab and mucosal healing in patients with inflammatory bowel diseases.},
  author={X Roblin and Hubert Marotte and Melanie Rinaudo and Emilie Del Tedesco and Amelie Carla Moreau and Jean Marc Phelip and Christian Genin and Laurent Peyrin-Biroulet and St{\'e}phane Paul},
  journal={Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association},
  year={2014},
  volume={12 1},
  pages={80-84.e2}
}
BACKGROUND & AIMS Little is known about the association between pharmacokinetic features of adalimumab and mucosal healing in patients with inflammatory bowel disease (IBD). METHODS We conducted a cross-sectional study of 40 patients with Crohn's disease (CD) or ulcerative colitis (UC) who received adalimumab maintenance therapy and underwent endoscopic evaluation of disease activity and pharmacokinetic analysis (measurements of trough levels and antibodies against adalimumab). Patients in… CONTINUE READING
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