Association between nasal carriage of Staphylococcus aureus and infection in liver transplant recipients.

@article{Bert2000AssociationBN,
  title={Association between nasal carriage of Staphylococcus aureus and infection in liver transplant recipients.},
  author={Frédéric Bert and J O Galdbart and Virginie Zarrouk and J Le M{\'e}e and François Durand and France Mentr{\'e} and Jacques Belghiti and Nicole Lambert-Zechovsky and Bruno Fantin},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2000},
  volume={31 5},
  pages={
          1295-9
        }
}
  • F. Bert, J. Galdbart, +6 authors B. Fantin
  • Published 15 November 2000
  • Medicine, Biology
  • Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
We reviewed the records of 87 patients who underwent liver transplantation and who were screened by use of nasal swabs on the day before surgery. Twenty-four patients harbored methicillin-susceptible Staphylococcus aureus (MSSA), and 8 harbored methicillin-resistant S. aureus (MRSA). MSSA infection occurred in 3 (12.5%) of 24 MSSA carriers and in 2 (3.2%) of 63 noncarriers (nonsignificant). In contrast, MRSA infection occurred more frequently in MRSA carriers (7 [87.5%] of 8) than in MRSA… 
View on PubMed
academic.oup.com
69 Citations
Highly Influential Citations
4
Background Citations
22
Methods Citations
2
Results Citations
1

69 Citations

Citation Type

Citation Type

Staphylococcus Aureus Rectal Carriage and its Association with Infections in Patients in a Surgical Intensive Care Unit and a Liver Transplant Unit
TLDR
Rectal carriage represents an underappreciated reservoir for S. aureus in patients in the intensive care unit and liver transplant recipients, and rectal plus nasal carriage may portend a greater risk for S-Aureus infections in these patients than currently realized.
Risk factors for Staphylococcus aureus infection in liver transplant recipients
  • F. Bert, C. Bellier, +5 authors B. Fantin
  • Medicine, Biology
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
  • 2005
TLDR
Preoperative nasal carriage of MRSA and MSSA is an independent risk factor for S. aureus infection in liver transplant recipients and molecular typing showed that the infecting isolate was identical to the isolate from the nose in most patients.
Carriage of methicillin‐resistant Staphylococcus aureus is associated with an increased risk of infection after liver transplantation
TLDR
Patients carrying MRSA are predisposed to an increased risk of sepsis after liver transplantation with a trend to increased mortality, and screening for MRSA should be considered in high‐risk patients being assessed for liver transplants.
Risk Factors for Methicillin Resistant Staphylococcus Aureus Infection in Liver Transplant Recipients
Colonization with methicillin‐resistant Staphylococcus aureus after liver transplantation
  • G. Santoro-Lopes, E. F. de Gouvêa, +8 authors J. Ribeiro-Filho
  • Medicine, Biology
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
  • 2005
TLDR
periodic postoperative screening for MRSA carriage should be an integral component in programs designed to reduce nosocomial MRSA transmission in patients receiving orthotopic liver transplantation (OLT).
Methicillin-resistant Staphylococcus aureus infection in liver transplantation: a matched controlled study.
The outcomes of methicillin-resistant Staphylococcus aureus infection after living donor liver transplantation in a Japanese center
TLDR
MRSA infection was a contributing factor in death after transplantation in cases with poor pretransplant status and linezolid was effective even for treating systemic MRSA infection after LDLT.
Staphylococcus aureus infections after liver transplantation
TLDR
Only recent surgical procedure was found to be a significant independent risk factor for S. aureus infections after liver transplantation, and it was not powered for such outcomes.
Lack of efficacy of mupirocin in the prevention of infections with staphylococcus aureus in liver transplant recipients and candidates1
TLDR
Elimination of S. aureus nasal carriage by mupirocin did not prevent S.aureus infections in patients in the liver transplant unit.
The risk of infection after nasal colonization with Staphylococcus aureus.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 41 REFERENCES
Staphylococcus aureus nasal colonization and association with infections in liver transplant recipients.
TLDR
MRSA colonization of the anterior nares was a significant predictor of MRSA infections in liver transplant recipients and was significantly associated with the carrier state.
Staphylococcus aureus nasal colonization in patients with cirrhosis: prospective assessment of association with infection.
OBJECTIVE To determine if Staphylococcus aureus colonization of the anterior nares was a risk factor for S aureus infection in patients with cirrhosis and to determine the predictors of S aureus…
Nosocomial Staphylococcus aureus bacteremia among nasal carriers of methicillin-resistant and methicillin-susceptible strains.
Staphylococcus aureus nasal carriage in 104 cirrhotic and control patients. A prospective study.
Methicillin-resistant staphylococcal colonization and infection in a long-term care facility.
OBJECTIVE To determine the natural history of colonization by methicillin-resistant Staphylococcus aureus (MRSA) among patients in a long-term care facility. We specifically sought to determine if…
Nasal mupirocin ointment decreases the incidence of Staphylococcus aureus bacteraemias in haemodialysis patients.
  • J. Boelaert, H. V. Van Landuyt, +7 authors L. Herwaldt
  • Medicine, Biology
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
  • 1993
TLDR
Chemoprophylaxis with nasal mupirocin in haemodialysis patients is cost-effective and leads to eradication of nasal S. aureus from the nares did not lead to overgrowth by other micro-organisms.
Bacterial infection as a complication of liver transplantation: epidemiology and risk factors.
TLDR
A retrospective survey was undertaken to characterize the epidemiology of bacterial infection in 79 patients who underwent 103 operations for orthotopic liver transplantation and identified prolonged duration of surgery and an elevated bilirubin level as risk factors for early bacterial infection at any site.
Hong Kong strains of methicillin-resistant and methicillin-sensitive Staphylococcus aureus have similar virulence.
Reduction of surgical-site infections in cardiothoracic surgery by elimination of nasal carriage of Staphylococcus aureus.
TLDR
The results of this study indicate that perioperative elimination of nasal carriage using mupirocin nasal ointment significantly reduces the SSI rate in cardiothoracic surgery patients and warrants a prospective, randomized, placebo-controlled efficacy trial.
Bacterial and fungal infections after liver transplantation: An analysis of 284 patients
TLDR
A prospective study of bacterial and fungal infections after liver transplantation in 284 adults found patients with acute liver failure were more prone to bacterial, but not fungal, infection and no associations were found between infections and duration of surgery.
...
1
2
3
4
5
...