Association between nasal carriage of Staphylococcus aureus and the human complement cascade activator serine protease C1 inhibitor (C1INH) valine vs. methionine polymorphism at amino acid position 480.

@article{Emonts2007AssociationBN,
  title={Association between nasal carriage of Staphylococcus aureus and the human complement cascade activator serine protease C1 inhibitor (C1INH) valine vs. methionine polymorphism at amino acid position 480.},
  author={Marieke Emonts and Christa E de Jongh and Jeanine J. Houwing-Duistermaat and Willem B. van Leeuwen and Ronald de Groot and Henri A. Verbrugh and Peter Hermans and Alex van Belkum},
  journal={FEMS immunology and medical microbiology},
  year={2007},
  volume={50 3},
  pages={330-2}
}
Staphylococcus aureus produces compounds that interfere with complement deposition. We hypothesized that humans have developed countermeasures to staphylococcal complement evasion and we screened for single nucleotide polymorphisms in the serine protease C1 inhibitor (C1INH) gene at amino acid position 480 (valine vs. methionine) and nasal carriage of S… CONTINUE READING