Association between mutation of the NF2 gene and monosomy 22 in menopausal women with sporadic meningiomas

@inproceedings{Tabernero2013AssociationBM,
  title={Association between mutation of the NF2 gene and monosomy 22 in menopausal women with sporadic meningiomas},
  author={Mar{\'i}a Dolores Tabernero and Mar{\'i}a Jara-Acevedo and Ana Bel{\'e}n Nieto and Arancha Rodr{\'i}guez Caballero and {\'A}lvaro Otero and Pablo Sousa and Jes{\'u}s M. Gonçalves and Patr{\'i}cia Henriques Domingues and Alberto Orfao},
  booktitle={BMC Medical Genetics},
  year={2013}
}
Meningioma was the first solid tumor shown to contain a recurrent genetic alteration e.g. monosomy 22/del(22q), NF2 being the most relevant gene involved. Although monosomy 22/del(22q) is present in half of all meningiomas, and meningiomas frequently carry NF2 mutations, no study has been reported so far in which both alterations are simultaneously assessed… CONTINUE READING