Association between morphologic CT imaging traits and prognostically relevant gene signatures in women with high-grade serous ovarian cancer: a hypothesis-generating study.

@article{Vargas2015AssociationBM,
  title={Association between morphologic CT imaging traits and prognostically relevant gene signatures in women with high-grade serous ovarian cancer: a hypothesis-generating study.},
  author={Hebert Alberto Vargas and Maura Micc{\`o} and Seong Im Hong and Debra A Goldman and Fanny Dao and Britta Weigelt and Robert A Soslow and Hedvig Hricak and Douglas A. Levine and Evis Sala},
  journal={Radiology},
  year={2015},
  volume={274 3},
  pages={742-51}
}
PURPOSE To investigate associations among imaging traits observed on computed tomographic (CT) images, Classification of Ovarian Cancer (CLOVAR) gene signatures, and survival in women with high-grade serous ovarian cancer (HGSOC). MATERIALS AND METHODS The institutional review board approved this HIPAA-compliant retrospective study of CT images obtained before cytoreductive surgery in 46 women with HGSOC, whose tumors were subjected to molecular analysis performed by the Cancer Genome Atlas… CONTINUE READING
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