Association between maternal COMT gene polymorphisms and fetal neural tube defects risk in a Chinese population.


UNLABELLED Maternal tea consumption was reported to increase the risk of fetal neural tube defects (NTDs). Catechol-O-methyltransferase (COMT) may be involved in the metabolism of polyphenolic methylation of tea, thus influence the risk of fetal NTDs. METHODS A total of 576 fetuses or newborns with NTDs and 594 healthy newborns were included in the case… (More)
DOI: 10.1002/bdra.23208