Association between lung cancer and microsomal epoxide hydrolase genotypes.

@article{Benhamou1998AssociationBL,
  title={Association between lung cancer and microsomal epoxide hydrolase genotypes.},
  author={Simone Benhamou and M Reinikainen and Christine Bouchardy and Pierre Dayer and Ari P Hirvonen},
  journal={Cancer research},
  year={1998},
  volume={58 23},
  pages={5291-3}
}
Microsomal epoxide hydrolase (mEH) is involved in the metabolism of tobacco-derived carcinogens. Polymorphisms in exons 3 and 4 of the EPHX gene have been reported to be associated with variations in mEH activity. We examined whether the predicted mEH activity modified the lung cancer risk among 150 cases and 172 controls, all French Caucasian smokers. A… CONTINUE READING