Association between lack of angiogenic response in muscle tissue and high expression of angiostatic ELR-negative CXC chemokines in patients with juvenile dermatomyositis: possible link to vasculopathy.

@article{Fall2005AssociationBL,
  title={Association between lack of angiogenic response in muscle tissue and high expression of angiostatic ELR-negative CXC chemokines in patients with juvenile dermatomyositis: possible link to vasculopathy.},
  author={Ndate Fall and Kevin E. Bove and K. Stringer and Daniel J. Lovell and Hermine I Brunner and Jennifer L. Weiss and Gloria C. Higgins and Susanne L Bowyer and Thomas Brent Graham and Sherry Thornton and Alexei A. Grom},
  journal={Arthritis and rheumatism},
  year={2005},
  volume={52 10},
  pages={
          3175-80
        }
}
OBJECTIVE To investigate the relationship between the vasculopathy of juvenile dermatomyositis (juvenile DM) and the balance between the angiostatic ELR- and angiogenic ELR+ CXC chemokines in the muscle of patients with the disease. METHODS The expression of 3 ELR- CXC chemokines (interferon-inducible protein 10 [IP-10], monokine induced by interferon-gamma, and interferon-inducible T cell alpha-chemoattractant) and 2 ELR+ CXC chemokines was quantitated in muscle biopsy samples from 7… CONTINUE READING
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