Association between inflammatory markers and the interleukin-6 -174 G/C polymorphism is abolished in peripheral arterial occlusive disease.

@article{Potaczek2007AssociationBI,
  title={Association between inflammatory markers and the interleukin-6 -174 G/C polymorphism is abolished in peripheral arterial occlusive disease.},
  author={Daniel Piotr Potaczek and Anetta Undas and Tomasz Nowakowski and Andrzej Szczeklik},
  journal={International angiology : a journal of the International Union of Angiology},
  year={2007},
  volume={26 4},
  pages={318-23}
}
AIM The interleukin-6 (IL-6) -174 G/C polymorphism has been reported to determine IL-6 levels and contribute to the development of cardiovascular disorders. The aim of our study was to evaluate the effect of the IL-6 -174 G/C polymorphism on hemostatic or inflammatory markers in patients with peripheral arterial occlusive disease (PAOD), a common manifestation of obliterative atherosclerosis. METHODS Plasma IL-6, fibrinogen, C-reactive protein (CRP), tissue plasminogen activator, plasminogen… CONTINUE READING