Association between in vivo alcohol metabolism and genetic variation in pathways that metabolize the carbon skeleton of ethanol and NADH reoxidation in the alcohol challenge twin study.

@article{Lind2012AssociationBI,
  title={Association between in vivo alcohol metabolism and genetic variation in pathways that metabolize the carbon skeleton of ethanol and NADH reoxidation in the alcohol challenge twin study.},
  author={Penelope A. Lind and Stuart Macgregor and A Christopher Heath and Pamela A. F. Madden and Grant W. Montgomery and Nicholas G. Martin and John B. Whitfield},
  journal={Alcoholism, clinical and experimental research},
  year={2012},
  volume={36 12},
  pages={2074-85}
}
BACKGROUND Variation in alcohol metabolism affects the duration of intoxication and alcohol use. While the majority of genetic association studies investigating variation in alcohol metabolism have focused on polymorphisms in alcohol or aldehyde dehydrogenases, we have now tested for association with genes in alternative metabolic pathways that catalyze the carbon skeleton of ethanol (EtOH) and NADH reoxidation. METHODS Nine hundred fifty single nucleotide polymorphisms (SNPs) spanning 14… CONTINUE READING
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Functionelle und Morphologische Organisation der Zelle. Springer-Varlag, Berlin

  • P Borst
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