Association between idiopathic infantile macrocephaly and autism spectrum disorders

@article{Bolton2001AssociationBI,
  title={Association between idiopathic infantile macrocephaly and autism spectrum disorders},
  author={Patrick F. Bolton and Monique J Roobol and Lesley Allsopp and Andrew J. Pickles},
  journal={The Lancet},
  year={2001},
  volume={358},
  pages={726-727}
}
We conducted a case-controlled, catch-up study of a cohort of boys born with macrocephaly in order to determine whether infantile macrocephaly is a risk marker for the later development of autism spectrum disorders. Our results show that infantile macrocephaly was associated with an increased risk of developing autism spectrum disorders (odds ratio 5.44, 95% CI 1.11-52.15; p=0.03). These findings suggest that neurobiological differences during infancy may predict behavioural manifestations of… CONTINUE READING
BETA

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 20 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-4 OF 4 REFERENCES

Autism screening questionnaire : diagnostic validity

  • S Chakrabarti, E Fombonne
  • Br J Psychiatry
  • 1999

Microcephaly and macrocephaly in autism

  • M Morgan, S Chinn
  • J Autism Dev Disord
  • 1999

A clinicopathological study of autism

  • E Fombonne, B Roge, J Claverie, S Courty, J Fremolle
  • Brain
  • 1998

Similar Papers

Loading similar papers…