Association between hypermethylation of DNA repetitive elements in white blood cell DNA and pancreatic cancer.

@article{Neale2014AssociationBH,
  title={Association between hypermethylation of DNA repetitive elements in white blood cell DNA and pancreatic cancer.},
  author={Rachel E Neale and P. D. J. Clark and Jonathan W Fawcett and Lin Fritschi and Belinda N. Nagler and Harvey A. Risch and Rhiannon J. Walters and William J. Crawford and Penelope M Webb and David C Whiteman and Daniel D Buchanan},
  journal={Cancer epidemiology},
  year={2014},
  volume={38 5},
  pages={576-82}
}
Pancreatic cancer is a leading cause of cancer-related deaths worldwide. Methylation of DNA may influence risk or be a marker of early disease. The aim of this study was to measure the association between methylation of three DNA repetitive elements in white blood cell (WBC) DNA and pancreatic cancer. DNA from WBCs of pancreatic cancer cases (n=559) and healthy unrelated controls (n=603) were tested for methylation of the LINE-1, Alu and Sat2 DNA repetitive elements using MethyLight… CONTINUE READING
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