Association between human papillomavirus (HPV) and oesophageal squamous cell carcinoma: a meta-analysis

  title={Association between human papillomavirus (HPV) and oesophageal squamous cell carcinoma: a meta-analysis},
  author={Hilary Hardefeldt and Michael R Cox and Guy D. Eslick},
  journal={Epidemiology and Infection},
  pages={1119 - 1137}
SUMMARY The oncogenic potential of human papillomaviruses (HPV) is well known in the context of cervical carcinoma; however, their role in the development of oesophageal squamous cell carcinoma (OSCC) is less clear. We aimed to determine the extent of the association between HPV infection and OSCC. A comprehensive literature search found 132 studies addressing HPV and OSCC in human cases, and a meta-analysis was performed using a random-effects model. There was evidence of an increased risk of… 
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The analysis result suggested the HPV prevalence in the esophageal cancer samples of China and clued the possible etiological relationships between HPV infection and the esophileal cancer development.
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