Association between hemolysis and albuminuria in adults with sickle cell anemia.

@article{Day2012AssociationBH,
  title={Association between hemolysis and albuminuria in adults with sickle cell anemia.},
  author={Thomas G Day and Emma R Dra{\vs}ar and Tony J Fulford and Claire C Sharpe and Swee Lay Thein},
  journal={Haematologica},
  year={2012},
  volume={97 2},
  pages={
          201-5
        }
}
Studies have questioned whether renal dysfunction in sickle cell disease is linked to hemolysis-associated vasculopathy. We have investigated renal function and markers of hemolysis in a cohort of 424 adult African-British patients with sickle cell disease. While significant associations were found in HbSS and HbSβ(0) (sickle cell anemia) patients with and without controlling for covariates between hemolytic markers and albuminuria, the associations were not significant in patients with HbSC… CONTINUE READING

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