Association between glutathione S-transferase polymorphisms and triglycerides and HDL-cholesterol.

@article{Maciel2009AssociationBG,
  title={Association between glutathione S-transferase polymorphisms and triglycerides and HDL-cholesterol.},
  author={Simone dos Santos Maciel and Alexandre da Costa Pereira and Gustavo Jos{\'e} Justo Da Silva and Mariliza Velho Rodrigues and Jos{\'e} Geraldo Mill and Jos{\'e} Eduardo Krieger},
  journal={Atherosclerosis},
  year={2009},
  volume={206 1},
  pages={204-8}
}
OBJECTIVE Null genotypes of glutathione S-transferase (GSTs) exhibit absence of enzymatic activity and are hypothesized to modulate an increased risk of developing cardiovascular disease. The aim of this study was to identify the potential association between GSTM1 and GSTT1 deleted polymorphisms with cardiovascular risk factors and coronary atherosclerosis in two independent urban populations. METHODS AND RESULTS Genotype distribution of GSTM1 and GSTT1 deleted polymorphism were examined in… CONTINUE READING