Association between genital schistosomiasis and HIV in rural Zimbabwean women
@article{Kjetland2006AssociationBG, title={Association between genital schistosomiasis and HIV in rural Zimbabwean women}, author={Eyrun F Kjetland and Patricia D Ndhlovu and Exenevia Gomo and Takafira Mduluza and Nicholas Midzi and Lovemore Gwanzura and Peter R. Mason and Leiv Sandvik and Henrik Friis and Svein Gunnar Gundersen}, journal={AIDS}, year={2006}, volume={20}, pages={593–600} }
Objective:To determine the association between female genital Schistosoma haematobium infection and HIV. Design and methods:A cross-sectional study with a 1-year follow-up. Gynecological and laboratory investigations were performed for S. haematobium and HIV. Sexually transmitted infections, demographic and urogenital history were analysed as confounders. The participants were 527 sexually active, non-pregnant, non-menopausal women between the ages of 20 and 49 years. The setting was a rural…
359 Citations
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It was revealed that pregnant women did not, on average, have a higher prevalence or intensity of infection of urinary schistosomiasis than non-pregnant women, and healthcare providers should be informed to consider treatment of pregnant women infected with schistomiasis during antenatal visits and whenever there is mass drug administration as recommended by the WHO.
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Schistosome infections were associated with increased transmission of HIV from both sexes, acquisition of HIV in women, and increased progression to death in HIV+ women, so establishing effective prevention and treatment strategies for schistosomiasis may reduce HIV incidence and death inAIDS+ persons living in endemic areas.
Association Between Schistosoma haematobium Exposure and Human Immunodeficiency Virus Infection Among Females in Mozambique.
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In logistic regression analyses predicting HIV-positive status, it is shown that exposure increases the odds of HIV- positive status by three times, controlling for demographic and sexual risk factors.
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Intestinal schistosomiasis in adult women was associated with systemic immune alterations, suggesting that associations with immunological correlates of HIV susceptibility warrant further investigation.
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