Association between genital schistosomiasis and HIV in rural Zimbabwean women

@article{Kjetland2006AssociationBG,
  title={Association between genital schistosomiasis and HIV in rural Zimbabwean women},
  author={Eyrun F Kjetland and Patricia D Ndhlovu and Exenevia Gomo and Takafira Mduluza and Nicholas Midzi and Lovemore Gwanzura and Peter R. Mason and Leiv Sandvik and Henrik Friis and Svein Gunnar Gundersen},
  journal={AIDS},
  year={2006},
  volume={20},
  pages={593–600}
}
Objective:To determine the association between female genital Schistosoma haematobium infection and HIV. Design and methods:A cross-sectional study with a 1-year follow-up. Gynecological and laboratory investigations were performed for S. haematobium and HIV. Sexually transmitted infections, demographic and urogenital history were analysed as confounders. The participants were 527 sexually active, non-pregnant, non-menopausal women between the ages of 20 and 49 years. The setting was a rural… 
Female Genital Schistosomiasis and HIV-1 Incidence in Zambian Women: A Retrospective Cohort Study
TLDR
Despite higher HIV seroconversion rates in women with FGS, there was no statistical evidence of association with HIV-1 acquisition among women with ≥2 positive genital PCR specimens, possibly due to low power.
Prevalence of urinary schistosomiasis and HIV in females living in a rural community of Zimbabwe: does age matter?
Cervicovaginal Immune Activation in Zambian Women With Female Genital Schistosomiasis
TLDR
FGS may alter the female genital tract immune environment, but larger studies in areas of varying endemicity are needed to evaluate the association with HIV-1 vulnerability.
Association of schistosomiasis and HIV infections: A systematic review and meta-analysis
  • P. Patel, C. Rose, W. Secor
  • Medicine
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
  • 2020
Urogenital schistosomiasis in women of reproductive age in Tanzania's Lake Victoria region.
TLDR
The data support the postulate that FUS may be a risk factor for HIV infection and may contribute to the extremely high rates of HIV among young women in sub-Saharan Africa.
Urogenital schistosomiasis in women of reproductive age and pregnant mothers in Kwale County, Kenya.
TLDR
It was revealed that pregnant women did not, on average, have a higher prevalence or intensity of infection of urinary schistosomiasis than non-pregnant women, and healthcare providers should be informed to consider treatment of pregnant women infected with schistomiasis during antenatal visits and whenever there is mass drug administration as recommended by the WHO.
Genital schistosomiasis in women: a clinical 12-month in vivo study following treatment with praziquantel.
Schistosomiasis is associated with incident HIV transmission and death in Zambia
TLDR
Schistosome infections were associated with increased transmission of HIV from both sexes, acquisition of HIV in women, and increased progression to death in HIV+ women, so establishing effective prevention and treatment strategies for schistosomiasis may reduce HIV incidence and death inAIDS+ persons living in endemic areas.
Association Between Schistosoma haematobium Exposure and Human Immunodeficiency Virus Infection Among Females in Mozambique.
TLDR
In logistic regression analyses predicting HIV-positive status, it is shown that exposure increases the odds of HIV- positive status by three times, controlling for demographic and sexual risk factors.
Schistosoma mansoni infection and socio-behavioural predictors of HIV risk: a cross-sectional study in women from Uganda
TLDR
Intestinal schistosomiasis in adult women was associated with systemic immune alterations, suggesting that associations with immunological correlates of HIV susceptibility warrant further investigation.
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