Association between genetic polymorphisms in folate-related enzyme genes and infertile men with non-obstructive azoospermia.

@article{Kim2015AssociationBG,
  title={Association between genetic polymorphisms in folate-related enzyme genes and infertile men with non-obstructive azoospermia.},
  author={Shin Y Kim and Jung Wook Lim and Jin Woo Kim and So-Yeon Park and Ju Tae Seo},
  journal={Systems biology in reproductive medicine},
  year={2015},
  volume={61 5},
  pages={
          286-92
        }
}
Polymorphisms in the genes encoding enzymes in the folate metabolism pathway have been associated with male infertility and chromosome abnormalities. The aim of this study was to analyze the distribution of the methylenetetrahydrofolate reductase (MTHFR), methionine synthase (MTR), and methionine synthase reductase (MTRR) polymorphisms in fertile men and infertile men with non-obstructive azoospermia (NOA). A case-control study comprising 85 infertile men with NOA and 246 fertile men as… CONTINUE READING
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