Association between estrogen receptor gene polymorphisms and curve severity of idiopathic scoliosis.

@article{Inoue2002AssociationBE,
  title={Association between estrogen receptor gene polymorphisms and curve severity of idiopathic scoliosis.},
  author={Masatoshi Inoue and Shohei Minami and Yoshinori Nakata and Hiroshi Kitahara and Yoshinori Otsuka and Keijiro Isobe and Masashi Takaso and Makoto Tokunaga and Shinsuke Nishikawa and Tetsuro Maruta and Hideshige Moriya},
  journal={Spine},
  year={2002},
  volume={27 21},
  pages={2357-62}
}
STUDY DESIGN Analysis of the estrogen receptor gene of girls with idiopathic scoliosis. OBJECTIVES To determine whether estrogen receptor gene polymorphisms correlate with curve severity of adolescent idiopathic scoliosis. SUMMARY OF BACKGROUND DATA Studies suggest that idiopathic scoliosis is a familial condition and that curve progression is related to genetically determined factors, such as skeletal and sexual growth. METHODS A total of 304 girls with idiopathic scoliosis were followed… CONTINUE READING