Association between estrogen receptor alpha (ESR1) gene polymorphisms and severe preeclampsia.

@article{Molvarec2007AssociationBE,
  title={Association between estrogen receptor alpha (ESR1) gene polymorphisms and severe preeclampsia.},
  author={Attila Molvarec and Agota V{\'e}r and Andrea Fekete and Kl{\'a}ra Rosta and L{\'a}szl{\'o} Derzbach and Zolt{\'a}n Derzsy and Istv{\'a}n Kar{\'a}di and J{\'a}nos Rig{\'o}},
  journal={Hypertension research : official journal of the Japanese Society of Hypertension},
  year={2007},
  volume={30 3},
  pages={205-11}
}
Associations have been reported between estrogen receptor alpha (ESR1) gene polymorphisms and various pathological conditions, including cardiovascular diseases. Our aim was to investigate whether two polymorphisms of the ESR1 gene (ESR1 c.454 -397T>C: PvuII restriction site and c.454 -351A>G: XbaI restriction site) are associated with preeclampsia. In a case-control study, we analyzed blood samples from 119 severely preeclamptic patients and 103 normotensive, healthy pregnant women using the… CONTINUE READING

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