Association between early promoter-specific DNA methylation changes and outcome in older acute myeloid leukemia patients.

Abstract

Treatment options for older patients with acute myeloid leukemia (AML) range from supportive care alone to full-dose chemotherapy. Identifying factors that predict response to therapy may help increase efficacy and avoid toxicity. The phase II SWOG S0703 study investigated the use of hydroxyurea and azacitidine with gemtuzumab ozogamicin in the elderly AML… (More)
DOI: 10.1016/j.leukres.2016.01.004

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Cite this paper

@article{Achille2016AssociationBE, title={Association between early promoter-specific DNA methylation changes and outcome in older acute myeloid leukemia patients.}, author={Nicholas J. Achille and Megan K.D. Othus and Kathleen M Phelan and Shubin Zhang and Kathrine Cooper and John E. Godwin and Frederick R Appelbaum and Jerald P Radich and H. P. Erba and Sucha Nand and Nancy J. Zeleznik-Le}, journal={Leukemia research}, year={2016}, volume={42}, pages={68-74} }