Association between duodenal contents reflux and squamous cell carcinoma--establishment of an esophageal cancer cell line derived from the metastatic tumor in a rat reflux model.

@article{Chen2007AssociationBD,
  title={Association between duodenal contents reflux and squamous cell carcinoma--establishment of an esophageal cancer cell line derived from the metastatic tumor in a rat reflux model.},
  author={Kuan-Hao Chen and Ken-ichi Mukaisho and Zhi-Qiang Ling and Akihiko Shimomura and Hiroyuki Sugihara and Takanori Hattori},
  journal={Anticancer research},
  year={2007},
  volume={27 1A},
  pages={175-81}
}
Squamous cell carcinoma (SCC) of the human esophagus has a multifactorial etiology involving several environmental and/or genetic factors. Recently, gastroesophageal reflux has been implicated as a causative factor in upper aerodigestive tract carcinogenesis. The development of esophageal squamous cell carcinoma (ESCC) in a duodenal contents reflux model without any known carcinogen present has been reported previously. In this study, the duodenal contents reflux model without gastrectomy was… CONTINUE READING

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Bile reflux as possible risk factor in laryngopharyngeal inflammatory and neoplastic lesions.

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