Association between dopamine beta hydroxylase gene polymorphism and age at onset in male schizophrenia

  title={Association between dopamine beta hydroxylase gene polymorphism and age at onset in male schizophrenia},
  author={I. {\"O}. Barlas and U. Semiz and M. Erdal and Ayhan Alg{\"u}l and O. I. Ay and M. A. Ateş and H. Çamdeviren and C. Başoǧlu and H. Herken},
  journal={Acta Neuropsychiatrica},
  pages={176 - 182}
  • I. Ö. Barlas, U. Semiz, +6 authors H. Herken
  • Published 2012
  • Medicine, Psychology
  • Acta Neuropsychiatrica
  • Objectives: The heterogeneity of schizophrenia mainly results from variations in clinical expressions of the disease, such as age at onset, gender differences in onset of illness, symptoms and response to antipsychotic treatment. Enhanced sensitisation of dopamine pathways in males, having consistently an earlier onset, might be implicated as disease modifiers for schizophrenia in males. Methods: In this study, we performed a case (n = 87)-control (n = 100) association study between the DBH5… CONTINUE READING
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