Association between disruption of CD4 receptor dimerization and increased human immunodeficiency virus type 1 entry

Abstract

Human immunodeficiency virus (HIV) enters target cells by a membrane fusion process that involves a series of sequential interactions between its envelope glycoproteins, the CD4 receptor and CXCR4/CCR5 coreceptors. CD4 molecules are expressed at the cell surface of lymphocytes and monocytes mainly as monomers, but basal levels of CD4 dimers are also present… (More)
DOI: 10.1186/1742-4690-3-31

Topics

Cite this paper

@article{Bourgeois2006AssociationBD, title={Association between disruption of CD4 receptor dimerization and increased human immunodeficiency virus type 1 entry}, author={Rachel Bourgeois and Johanne Mercier and Isabelle Paquette-Brooks and {\'E}ric A Cohen}, journal={Retrovirology}, year={2006}, volume={3}, pages={31 - 31} }