Association between decreased WWOX protein expression and thyroid cancer development.

@article{Dias2007AssociationBD,
  title={Association between decreased WWOX protein expression and thyroid cancer development.},
  author={Eduardo Pimentel Dias and Fl{\'a}vio Juliano Garcia Santos Pimenta and Marta Maria S Sarquis and Marco Antonio Dias Filho and C. Marcelo Aldaz and Julienne Borges Fujii and Ricardo Santiago Gomez and Luiz De Marco},
  journal={Thyroid : official journal of the American Thyroid Association},
  year={2007},
  volume={17 11},
  pages={1055-9}
}
CONTEXT Chromosomal fragile sites are often related to cancer development. The WW domain-containing oxidoreductase gene (WWOX) spans the second most common chromosomal fragile site (FRA16D) and encodes an important proapoptotic protein. OBJECTIVE To verify our hypothesis that underexpression of WWOX could contribute to malignant transformation of the… CONTINUE READING