Association between cytosolic expression of BRCA1 and metastatic risk in breast cancer


Background:Although BRCA1 has been extensively studied for its role as a tumour-suppressor protein, the role of BRCA1 subcellular localisation in oncogenesis and tumour progression has remained unclear. This study explores the impact of BRCA1 mislocalisation on clinical outcomes in breast cancer.Methods:Tissue microarrays assembled from a cohort of patients… (More)
DOI: 10.1038/bjc.2015.208


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