Association between cytomegalovirus infection, enhanced proinflammatory response and low level of anti-hemagglutinins during the anti-influenza vaccination--an impact of immunosenescence.

@article{Trzonkowski2003AssociationBC,
  title={Association between cytomegalovirus infection, enhanced proinflammatory response and low level of anti-hemagglutinins during the anti-influenza vaccination--an impact of immunosenescence.},
  author={Piotr Trzonkowski and Jolanta Myśliwska and Ewa Szmit and Joanna Więckiewicz and Krzysztof Lukaszuk and Lidia Bernadeta Brydak and Magdałena K Machała and Andrzej Myśliwski},
  journal={Vaccine},
  year={2003},
  volume={21 25-26},
  pages={3826-36}
}
We assessed association between prior cytomegalovirus (CMV) infection, proinflammatory status and effectiveness of the anti-influenza vaccination. We examined 154 individuals during the epidemic season dividing them according to the age, response to the vaccine and the Senieur Protocol (SP). The anti-hemagglutinins (HI), tumour necrosis factor alpha (TNFalpha), interleukin (IL) 1beta, IL6, IL10, ACTH/cortisol axis, anti-CMV antibodies and CD28+CD57- lymphocytes were assessed. Non-responders of… CONTINUE READING
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