Association between complement regulatory protein factor H and AM34 antigen, detected in senile plaques.

@article{Honda2000AssociationBC,
  title={Association between complement regulatory protein factor H and AM34 antigen, detected in senile plaques.},
  author={Shigehiro Honda and Fumio Itoh and Maisa Yoshimoto and Shinji Ohno and Yuji Hinoda and Kenichi Imai},
  journal={The journals of gerontology. Series A, Biological sciences and medical sciences},
  year={2000},
  volume={55 5},
  pages={M265-9}
}
BACKGROUND We have previously shown that monoclonal antibody AM34, which is reactive with senile plaques, may recognize the C terminus of complement factor H. In this study, we investigated the expression of factor H in tissue from a human brain and the relation between AM34 antigen and factor H. METHOD Total ribonucleic acid (RNA) was extracted from a… CONTINUE READING