Association between coffee consumption and total dietary caffeine intake with cognitive functioning: cross-sectional assessment in an elderly Mediterranean population

  title={Association between coffee consumption and total dietary caffeine intake with cognitive functioning: cross-sectional assessment in an elderly Mediterranean population},
  author={I. Paz-Graniel and N. Babio and N. Becerra-Tom{\'a}s and E. Toledo and L. Camacho-Barcia and D. Corella and Olga Casta{\~n}er-Ni{\~n}o and D. Romaguera and J. Vioque and {\'A}. Alonso-G{\'o}mez and J. W{\"a}rnberg and J. Mart{\'i}nez and L. Serra-Majem and R. Estruch and F. Tinahones and F. Fern{\'a}ndez-Aranda and J. Lapetra and X. Pint{\'o} and J. Tur and A. Garc{\'i}a-R{\'i}os and A. Bueno-Cavanillas and J. Gaforio and P. Mat{\'i}a-Mart{\'i}n and L. Daimiel and V. S{\'a}nchez and J. Vidal and Luc{\'i}a Prieto-Sanchez and E. Ros and C. Razquin and C. Mestres and J. Sorl{\'i} and A. Cuenca-Royo and {\'A}ngel Rios and L. Torres-Collado and Jessica Vaquero-Luna and N. P{\'e}rez-Farin{\'o}s and M. Zulet and A. S{\'a}nchez-Villegas and R. Casas and M. Bernal-L{\'o}pez and J. M. Santos-Lozano and X. Corbella and D. Mateos and P. Buil-Cosiales and S. Jim{\'e}nez-Murcia and R. Fern{\'a}ndez-Carri{\'o}n and Laura Forcano-Gamazo and Meritxell L{\'o}pez and Miguel {\'A}ngel Sempere-Pascual and A. Moreno-Rodr{\'i}guez and A. Gea and R. De la Torre-Fornell and J. Salas-Salvad{\'o} and J. M. A. M. E. F. J. D. R. J. D. J. A. J. J. A. {\'A}. M. Salas-Salvad{\'o} Mart{\'i}nez-Gonz{\'a}lez Fit{\'o} Ros Tinahones and M. Mart{\'i}nez-Gonz{\'a}lez and M. Fit{\'o} and J. L{\'o}pez-Miranda and V. Mart{\'i}n and C. V{\'a}zquez and M. Delgado-Rodr{\'i}guez and M. Rubio and A. S{\'a}nchez-Ta{\'i}nta and H. Schr{\"o}der and A. Marcos and J. Warnberg and C. Botella and F. Ar{\'o}s and M. Ald{\'a}miz and L. Forga and A. Garc{\'i}a-Layana and J. Portu and J. Timiraos and A. Gonz{\'a}lez-Pinto and I. Zorrilla and M. Mart{\'i}nez-Kareaga and P. Seoane and A. G. Pinto and M. Martinez and M. Stampfer and J. Sabat{\'e} and A. Astrup and F. Fern{\'a}ndez-Avil{\'e}s and X. Pi-Sunyer and R. P. Llaberia and R. Gonz{\'a}lez and R. {\'A}lamo and F. P. Palleja and J. Balsells and J. M. Roca and T. B. Gallisa and J. Vizcaino and P. L. Alpizarte and C. Perpi{\~n}{\'a} and M. Vernet and C. Caballero and M. Barco and M. D. Mart{\'i}nez and J. G. Rossell{\'o} and A. Del Pozo and C. PobletCalaf and P. A. Zabal and X. Floresv{\'i} and M. Benet and A. Galindo and J. Vila and F. Andr{\'e}s and M. Soler and M. Vidal and J. Vilalta and J. Casajuana and M. Ricard and F. S{\'a}iz and A. Isach and M. M. S. Martinez and E. Font and C. Luque and C. Sola and G. Mestres and J. Basora and G. Mena-S{\'a}nchez and L. Pi{\~n}ol and M. Segura and N. Rosique-Esteban and S. Chig and I. Cano and V. Garc{\'i}a and C. G{\'o}mez-Mart{\'i}nez and L. L{\'o}pez-Gonz{\'a}lez and A. Salas-Huetos and J. Vallverd{\'u} and C. Garc{\'i}a and L. S. Niembro and P. Hern{\'a}ndez-Alonso and S. Canudas and A. D{\'i}az-L{\'o}pez and M. Ru{\'i}z-Canela and Z. V{\'a}zquez and M. Bes-Rastrollo and B. Aranguren and E. Go{\~n}i and L. Goni and M. J. Cobo and A. Rico-Camp{\`a} and F. J. B. Gortari and A. G. Arellano and J. D{\'i}ez-Espino and O. Lecea-Juarez and J. C. Cenoz-Osinaga and I. Alvarez-Alvarez and M. C. Say{\'o}n-Orea and C. Fernandez-L{\'a}zaro and L. Ruiz-Estigarribia and J. Bartolom{\'e}-Resano and A. Sola-Larraza and E. Lozano-Oloriz and B. Cano-Valles and S. Eguaras and E. P. Roquet-Jalmar and I. Galilea-Zabalza and H. Lancova and R. Ramallal and M. L. Garcia-Perez and V. Estremera-Urabayen and M. J. Ariz-Arnedo and C. Hijos-Larraz and C. Fernandez-Alfaro and B. I{\~n}igo-Mart{\'i}nez and R. Moreno and S. Mart{\'i}n-Almendros and L. Barandiaran-Bengoetxea and C. Fuertes-Go{\~n}i and A. Lezaun-Indurain and M. J. Guruchaga-Arcelus and O. Olmedo-Cruz and L. Escriche-Erviti and R. Ansorena-Ros and R. Sanmatin-Zabaleta and J. Apalategi-Lasa and J. Villanueva-Telleria and M. M. Hern{\'a}ndez-Espinosa and L. Herrera-Valdez and L. Dorronsoro-Dorronsoro and Lourdes Echeverria-Lizarraga and J. Cabeza-Beunza and P. Fern{\'a}ndez-Urretavizcaya and P. Gasc{\'o}-Garc{\'i}a and C. Royo-Jimenez and J. Moran-P{\'i} and F. Salazar-Fern{\'a}ndez and F. J. Chasco-Ros and F. Cort{\'e}s‐Ugalde and J. J. Jurio-Burgui and P. Pascual-Pascual and A. I. Rodr{\'i}guez-Ezpeleta and M. Esparza-C{\'a}ceres and C. Arroyo‐Azpa and M. R. de Galdeano and T. Forcen-Alonso and M. Armendariz-Marcotegui and A. Brugos-Larumbe and A. Arillo and B. L{\'o}pez-Aisa and J. I. Gonz{\'a}lez and O. Portol{\'e}s and C. Ortega-Azor{\'i}n and R. Barrag{\'a}n and E. M. Asensio and {\'O}. Coltell and R. Mart{\'i}nez-LaCruz and I. Gimenez-Alba and C. Saiz and R. Osma and E. F{\'e}rriz and I. Gonz{\'a}lez-Monje and P. Guillem-S{\'a}iz and F. Gim{\'e}nez-Fern{\'a}ndez and L. Quiles and P. Carrasco and A. Carratal{\'a}-Calvo and C. Valero-Barcel{\'o} and C. Mir and S. S{\'a}nchez-Navarro and J. Navas and I. Gonz{\'a}lez-Gallego and L. Bort-Llorca and L. P{\'e}rez-Ollero and M. Giner-Valero and R. Monfort-S{\'a}ez and J. Nadal-Sayol and V. Pascual-Fuster and M. Mart{\'i}nez-P{\'e}rez and C. Riera and M. Belda and A. Medina and E. Miralles and M. J. Ram{\'i}rez-Esplugues and M. Rojo-Furi{\'o} and G. Mattingley and M. A. Delgado and M. Pages and Y. Riofr{\'i}o and L. Abuomar and N. Blasco-Lafarga and R. Tosca and L. Liz{\'a}n and A. Valcarce and M. Medina and S. de Valc{\'a}rcel and N. Tormo and O. Felipe-Rom{\'a}n and S. Lafuente and E. Nav{\'i}o and G. Aldana and J. V. Crespo and J. Llosa and L. Gonz{\'a}lez-Garc{\'i}a and R. Casta{\~n}er and M. Mu{\~n}oz and M. D. Zome{\~n}o and {\'A}. Hern{\'a}ez and L. Torres and M. Quifer and R. Llimona and G. Freixer and K. P{\'e}rez-Vega and M. Farr{\`a}s and R. Elosua and I. Subirana and S. P{\'e}rez and A. Goday and J. J. Jordan and J. A. F. Lerroux and D. B. Boix and G. Llaurad{\'o} and M. Farr{\'e} and E. Menoyo and A. Aldea-Perona and M. P{\'e}rez-Otero and D. Mu{\~n}oz-Aguayo and S. Gaixas and G. Blanchart and A. Sanllorente and M. Soria and J. Valussi and A. Cuenca and L. Forcano and A. Pastor and A. Boronat and S. Tello and M. Caba{\~n}ero and L. Franco and R. de la Torre and C. Medrano and J. Bayo and M. T. Garc{\'i}a and V. Robledo and P. Babi and E. Canals and N. Soldevila and L. Carr{\'e}s and C. Roca and M. Comas and G. Gasulla and X. Herraiz and A. Mart{\'i}nez and E. Vinyoles and J. Verd{\'u} and M. M. Aguade and E. Massip and M. L. Grau and M. Mengual and V. Moldon and M. V. Vergaz and R. G{\'o}mez and Ciurana and M. Riu and A. Vidal and F. Pe{\~n}as and {\'A}. Raya and M. A. Sebastian and M. Valls and J. Guerrero and M. Marne and E. Minguella and M. Montenegro and A. Sala and M. R. Sen{\'a}n and N. Talens and N. Vera and M. Garc{\'i}a-de-la-Hera and E. M. Navarrete-Mu{\~n}oz and S. Gonz{\'a}lez-Palacios and L. Compa{\~n}-Gabucio and A. Oncina-Canovas and L. Notario-Barandiar{\'a}n and D. Orozco-Beltr{\'a}n and S. Mart{\'i}nez and A. Asensio and I. Candela-Garc{\'i}a and J. M. Zazo and C. G. Sell{\'e}s and N. Fern{\'a}ndis-Brufal and J. Maci{\'a} and C. Barcel{\'o} and M. C. Altozano-Rodado and N. Garc{\'i}a and M. C. M. Vergara and M. Pascual and S. Gisbert and A. Botella and C. M. Garc{\'i}a and R. V. Enguix and N. G. Bellvert and I. Aguilera and R. Maci{\'a}n and A. Morell and E. A. Bartolom{\'e} and J. Baixauli and M. S{\'a}nchez and B. Rojo and E. Perez and C. Maci{\'a} and L. A. M. Castej{\'o}n and I. G. Garc{\'i}a and M. Ballesta and C. Polo and E. Agull{\'o} and M. Fiol and M. Mo{\~n}ino and A. Colom and J. Konieczna and M. Morey and R. Zamanillo and A. M. Galm{\'e}s-Panad{\'e}s and V. Pereira and M. A. Mart{\'i}n and A. Y{\'a}{\~n}ez and J. Llobera and J. Ripoll and R. Prieto and F. Grases and A. Costa and C. Fern{\'a}ndez-Palomeque and E. Fortuny and M. Noris and S. Munuera and F. Tom{\'a}s and F. Fiol and A. Jover and J. Janer and C. Vallespir and I. Mattei and N. Feuerbach and M. del Mar Sureda and S. Vega and L. Quintana and A. Fiol and M. Amador and S. Gonz{\'a}lez and J. Coll and A. Moy{\'a} and T. P. Sistac and M. D. S. Fern{\'a}ndez and J. PouBordoy and I. Abete and I. Cantero and C. Cristobo and I. Ibero-Baraibar and J. {\'A}greda-Peir{\'o} and M. D. Lez{\'a}un-Burgui and N. Go{\~n}i-Ruiz and R. Bartolom{\'e}-Resano and E. Cano-C{\'a}ceres and T. Elcarte-L{\'o}pez and E. Echarte-Osacain and B. P{\'e}rez-Sanz and I. Blanco-Platero and A. Andueza-Azc{\'a}rate and A. Gimeno-Aznar and E. Urs{\'u}a-Sesma and B. Ojeda-Bilbao and J. Mart{\'i}nez-Jarauta and L. Ugalde-Sarasa and B. R{\'i}podas-Echarte and M. V. G{\"u}eto-Rubio and C. Napal-Lecumberri and M. D. Mart{\'i}nez-Mazo and E. Arina-Vergara and A. Parra-Os{\'e}s and F. Artal-Moneva and F. B{\'a}rcena-Amigo and F. Calle-Irastoza and J. Abad-Vicente and J. I. Armend{\'a}riz-Artola and P. I{\~n}igo-Cibrian and J. Escribano-Jarauta and J. Ulibarri-delportillo and B. Churio‐Beraza and Y. Monz{\'o}n-Mart{\'i}nez and E. Madoz-Zubillaga and C. Arr{\'o}niz and F. J. Bar{\'o}n-L{\'o}pez and J. F. Garc{\'i}a and N. Moreno-Morales and M. del C. Rodr{\'i}guez-Mart{\'i}nez and J. P{\'e}rez-L{\'o}pez and J. C. Benavente-Mar{\'i}n and E. Oliva and E. Fern{\'a}ndez and F. Gonz{\'a}lez and R. Moral and S. Moreno and M. Ruiz and M. Cornide and V. G{\'o}mez and J. C. Garc{\'i}a and A. Morales and J. Pe{\~n}a and F. J. G. Delgado and J. F. Alcal{\'a} and A. L. Acu{\~n}a and A. P. A. Larriva and F. R. Cantalejo and J. C. Villaraso and I. Eugenio and P. Carvajal and M. C. del Campo Molina and P. Orihuela and I. P. Corral and G. Navarro and M. Dom{\'e}nech and C. Vi{\~n}as and S. Castro-Barquero and A. M. Ruiz-Le{\'o}n and R. Losno and L. Tar{\`e}s and A. Jordan and R. Soriano and M. Camafort and C. Sierra and E. Sacanella and A. Sala-Vila and J. Cots and I. Sarroca and M. Garc{\'i}a and N. Berm{\'u}dez and A. P{\'e}rez and I. Duaso and A. de la Arada and R. Hern{\'a}ndez and C. Sim{\'o}n and M. de la Poza and I. Gil and M. Vil{\`a} and C. Iglesias and N. Assens and M. Amatller and L. Rams and T. Benet and G. Fern{\'a}ndez and J. Teruel and A. Azor{\'i}n and M. Cubells and D. L{\'o}pez and J. Llovet and M. L. G{\'o}mez and P. Climente and L. D. de Paula and J. Soto and C. Carbonell and C. Llor and X. Abat and A. Cama and M. Fortuny and C. Domingo and A. Liberal and T. Mart{\'i}nez and E. Ya{\~n}ez and M. J. Nieto and E. Lloret and C. Carrazoni and A. Belles and C. Olmos and M. Ramentol and M. Capell and I. Giner and A. Mu{\~n}oz and R. Mart{\'i}n and E. Mor{\'o}n and A. Bonillo and G. S{\'a}nchez and C. Calb{\'o} and J. Pous and M. Massip and Y. Garc{\'i}a and M. C. Massagu{\'e} and R. Ib{\'a}{\~n}ez and J. Llaona and T. Vidal and N. Vizcay and E. Segura and C. Galindo and M. Moreno and M. Caubet and J. Altirriba and G. Flux{\`a} and P. Toribio and E. Torrent and J. Ant{\'o}n and A. Viaplana and G. Vieytes and N. Duch and A. Pereira and E. Sant and J. Gen{\'e} and H. Calvillo and F. Pont and M. Puig and M. Casasayas and A. Garrich and E. Senar and I. Boix and E. Sequeira and V. Aragunde and S. Riera and M. Salgado and M. Fuentes and E. Martin and A. Ubieto and F. Pallar{\'e}s and C. Sala and A. Abilla and E. Mayor and T. Colom and A. Gaspar and A. Gomez and L. Palacios and R. Garrigosa and L. G. Molina and B. Gallego and N. C. Ib{\'a}{\~n}ez and A. Calvo and A. Maldonado and E. Garrido and A. Dominguez and F. G. Jim{\'e}nez and E. Carazo and A. J. T. Gonz{\'a}lez and F. Ruiz and J. M. Santiago and M. Bellon and A. S{\'a}nchez and L. Mir and R. R. Tapioles and F. D. Atienza and L. Camus and C. Martos and D. Lozano and M. Alc{\'a}zar and F. Diaz and M. C. Sierra and P. Cubero and A. Rodr{\'i}guez and F. Garcia and J. Molina and F. Rodr{\'i}guez and I. Salaverria and M. Bell{\'o} and L. Tojal and L. Goicolea and C. Sorto and A. Goikoetxea and A. Casanellas and M. A. Otero and J. O. M. De Arbulo and J. Morgado and J. R. Ollora and J. Urraca and M. Carrera and F. Toribio and E. Mag{\'a}n and S. Madrid and M. Merino and M. Jim{\'e}nez and M. Jodra and B. L. Alonso and J. I. Iriso and C. Romero and A. I. De La Guerra and M. Abbate and E. Angullo and E. Argelich and M. M. Bibiloni and C. Bouzas and X. Cap{\'o} and S. Carreres and L. Gallardo and J. M. G{\'a}mez and B. Garc{\'i}a and A. Julibert and C. G{\'o}mez and I. Llompart and A. Martorell and C. M. Mascar{\'o} and Monserrat and S. Montemayor and A. Pons and A. Pouso and J. Ramos and V. Ramos and T. Ripoll and T. Rodr{\'i}guez and L. Sanz and A. Sureda and S. Tejada and L. Ugarriza and M. L{\'o}pez and M. Gonz{\'a}lez and J. Nava and A. M. Garach and A. Banderas and A. V. Alarcon-Martin and M. D. de Mier and J. A. Torres and A. Candela and M. L. Fern{\'a}ndez and R. Robles and S. Fern{\'a}ndez and J. M. Mar{\'i}n and J. {\'A}lvarez-P{\'e}rez and E. M. D. Ben{\'i}tez and F. D{\'i}az-Collado and J. P{\'e}rez-Cabrera and L. T. Casa{\~n}as-Quintana and R. Garc{\'i}a-Guerra and I. Bautista-Casta{\~n}o and C. Ruano-Rodr{\'i}guez and F. S. de la Fe and J. A. Garc{\'i}a-Pastor and B. Mac{\'i}as-Guti{\'e}rrez and I. Falc{\'o}n-Sanabria and C. Sim{\'o}n-Garc{\'i}a and A. J. Santana-Santana and J. {\'A}lvarez-{\'A}lvarez and B. V. D{\'i}az-Gonz{\'a}lez and J. M. C. Anzalas and R. E. Sosa-Also and J. Medina-Ponce and S. A. Olea and L. {\'A}lvarez-{\'A}lvarez and A. Torres and P. Farias and N. Cubelos and A. AdlbiSibai and M. Ajenjo and E. CarriedoUle and M. E. Fern{\'a}ndez and J. I. F. Garc{\'i}a and J. F. V{\'a}zquez and C. G. Quintana and F. G. Rivero and M. L. Popescu and J. Gil and J. L. de la Iglesia and A. Delgado and C. Acevedo and S. R. Celada and M. Bul and E. F. Mielgo and L. Mir{\'o}-Moriano and C. Dom{\'i}nguez-Espinaco and S. Vaquero-D{\'i}az and F. Garcia-Corte and A. Santos-Calonge and C. Toro-Cort{\'e}s and N. Pelegrina-L{\'o}pez and V. Urbano-Fern{\'a}ndez and M. Ortega-Calvo and J. Lozano-Rodr{\'i}guez and I. Rivera-Ben{\'i}tez and M. Caballero-Valderrama and P. Iglesias-Bonilla and P. Rom{\'a}n-Torres and Y. Corchado-Albalat and L. Mellado-Mart{\'i}n and A. D. de Cos and S. Gutierrez and S. Artola and A. Gald{\'o}n and I. Gonzalo and A. Galera and M. Gimenez-Gracia and E. de la Cruz and R. Figueras and M. Poch and R. Freixedas and F. Trias and I. Sarasa and M. Fanlo-Maresma and H. Lafuente and M. Liceran and A. Rodr{\'i}guez-S{\'a}nchez and C. Pallarols and E. G{\'o}mez-S{\'a}nchez and V. Esteve-Luque and J. Monedero and E. Corbella and A. Alt{\'e}s and I. Vinagre and C. Mestre and J. Viaplana and M. Serra and J. Vera and T. Freitas and E. Ortega and I. Pla and R. Olbeyra and J. Ordovas and V. Mic{\'o} and L. Berninches and L. Diez and M. J. Concejo and J. Mu{\~n}oz and M. Adri{\'a}n and Y. de la Fuente and C. Albertos and M. L. Cornejo and C. Cuesta and A. Montero and J. Aroca and S. Moraleda and N. Li{\'e}tor and J. Peis and T. Ure{\~n}a and M. Rueda and C. Lopera and C. Isabel and M. A. Flores and M. D. de Diego and T. B. C{\'a}ceres and Y. P. Cereceda and M. M. Abad and R. C. V{\'e}lez and M. G. Cerrajero and M. A. R. Herrera and M. T. Ellacur{\'i}a and A. B. Bustelo and M. Ramos and {\'A}. Sainz and R. Ba{\~n}os and A. Garc{\'i}a-Palacios and G. Tormo and N. Esta{\~n}-Capell and A. Casal and L. Beltr{\'a}n and C. B. Morant and E. Iglesias and D. A. Leon and A. H. Espinilla and A. Herranz and S. S{\'a}ez and J. A. Herrero and J. Gayete and J. M. Ortega and M. Ayora and A. Moncho and S. M. de Andr{\'e}s and J. F. Navajas and M. Bedmar and A. G. Rodr{\'i}guez and A. M. Larrubia and M. C. Varo and C. Bravo and N. Mallorqu{\'i}-Bagu{\'e} and R. Granero and Z. Ag{\"u}era and M. Lozano-Madrid},
  journal={European Journal of Nutrition},
  pages={1 - 16}
Coffee is rich in compounds such as polyphenols, caffeine, diterpenes, melanoidins and trigonelline, which can stimulate brain activity. Therefore, the possible association of coffee consumption with cognition is of considerable research interest. In this paper, we assess the association of coffee consumption and total dietary caffeine intake with the risk of poor cognitive functioning in a population of elderly overweight/obese adults with metabolic syndrome (MetS). PREDIMED-plus study… Expand

Figures and Tables from this paper


Coffee consumption and cognitive function among older adults.
Does caffeine intake enhance absolute levels of cognitive performance?
  • M. Jarvis
  • Psychology, Medicine
  • Psychopharmacology
  • 2005
Relationships Between Caffeine Intake and Risk for Probable Dementia or Global Cognitive Impairment: The Women's Health Initiative Memory Study.
Coffee consumption and total mortality in a Mediterranean prospective cohort.