Association between circulating interleukin-1 beta (IL-1β) levels and IL-1β C–511T polymorphism with cervical cancer risk in Egyptian women

@article{AlTahhan2011AssociationBC,
  title={Association between circulating interleukin-1 beta (IL-1β) levels and IL-1β C–511T polymorphism with cervical cancer risk in Egyptian women},
  author={Magdy A. Al-Tahhan and Rasha Lotfi Etewa and Manal Mohamed El Behery},
  journal={Molecular and Cellular Biochemistry},
  year={2011},
  volume={353},
  pages={159-165}
}
Cancer cervix is one of the leading causes of cancer-related mortality among women worldwide. It is believed that the host genetic factors such as inflammation-induced cytokines may play a role in cervical carcinogenesis. The interleukin-1β (IL-1β) gene contains several single nucleotide polymorphisms. One of them, C–511T, which in the promoter region has been associated with increased IL-1β production and with increased risk of developing cancers. We assessed the association between the IL-1… CONTINUE READING
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