Association between circulating DNA, serum (1->3)-β-D-glucan, and pulmonary fungal burden in Pneumocystis pneumonia.

Abstract

Circulating Pneumocystis jirovecii DNA and (1→3)-β-d-glucan determined in 70 serum samples from immunocompromised patients were compared to fungal load in bronchoalveolar lavage fluids assessed using quantitative polymerase chain reaction. Both serum biomarkers are influenced by pulmonary fungal load, which should be taken into account when diagnosing Pneumocystis infection.

DOI: 10.1093/cid/cis412

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@article{Costa2012AssociationBC, title={Association between circulating DNA, serum (1->3)-β-D-glucan, and pulmonary fungal burden in Pneumocystis pneumonia.}, author={J M Costa and Françoise Botterel and Odile Cabaret and Françoise Foulet and Catherine Cordonnier and St{\'e}phane Bretagne}, journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America}, year={2012}, volume={55 2}, pages={e5-8} }