Association between childhood trauma and catecholamine response to psychological stress in police academy recruits

  title={Association between childhood trauma and catecholamine response to psychological stress in police academy recruits},
  author={Christian Otte and Thomas C. Neylan and Nnamdi Pole and Thomas J. Metzler and Suzanne R. Best and Clare Henn-Haase and Rachel Yehuda and Charles R Marmar},
  journal={Biological Psychiatry},

Pretraumatic prolonged elevation of salivary MHPG predicts peritraumatic distress and symptoms of post-traumatic stress disorder.

Childhood Trauma, Perceived Stress, and Hair Cortisol in Adults With and Without Cardiovascular Disease

Objective Childhood trauma has been associated with greater psychological and physical morbidity, including a greater risk of developing cardiovascular disease (CVD). This may partially reflect

Childhood Trauma Associated with Short Leukocyte Telomere Length in Posttraumatic Stress Disorder

Previous Trauma Exposure and PTSD Symptoms as Predictors of Subjective and Biological Response to Stress

Previous trauma and reduced social supports were associated with continuing psychological distress, confirming previous research and raising concerns about the cumulative negative effects of traumatic exposure on psychological health in emergency responders.

Associations between childhood trauma and emotion-modulated psychophysiological responses to startling sounds: a study of police cadets.

Results suggest that childhood trauma may lead to long-lasting alterations in emotional and psychophysiological reactivity even in the absence of current Axis I psychopathology.

Family psychiatric history, peritraumatic reactivity, and posttraumatic stress symptoms: a prospective study of police.

Does Posttraumatic Stress Disorder (PTSD) Affect Performance?

There is no reason to believe that police recruits with PTSD are prone to making errors of communication or judgment that would place them or others at increased risk.

GH response to intravenous clonidine challenge correlates with history of childhood trauma in personality disorder.




Pituitary-adrenal and autonomic responses to stress in women after sexual and physical abuse in childhood.

The findings suggest that hypothalamic-pituitary-adrenal axis and autonomic nervous system hyperreactivity, presumably due to CRF hypersecretion, is a persistent consequence of childhood abuse that may contribute to the diathesis for adulthood psychopathological conditions.

Higher Cortisol Levels Following Exposure to Traumatic Reminders in Abuse-Related PTSD

Results are consistent with higher cortisol levels following exposure to traumatic stressors in PTSD, and memory consolidation after the trauma scripts was impaired relative to baseline, with no association between memory performance and cortisol levels.

The role of early adverse experience and adulthood stress in the prediction of neuroendocrine stress reactivity in women: A multiple regression analysis

The findings suggest that a history of childhood abuse per se is related to increased neuroendocrine stress reactivity, which is further enhanced when additional trauma is experienced in adulthood.

Risk and resilience in posttraumatic stress disorder.

  • R. Yehuda
  • Psychology
    The Journal of clinical psychiatry
  • 2004
It is of interest why certain individuals are at risk for development of PTSD after traumatic exposure, whereas others appear to be more resilient to the effects of trauma.

Neurobiological consequences of childhood trauma.

  • C. Nemeroff
  • Psychology, Biology
    The Journal of clinical psychiatry
  • 2004
Preclinical and clinical studies have shown that repeated early-life stress leads to alterations in central neurobiological systems, particularly in the corticotropin-releasing factor system, leading to increased responsiveness to stress.

Childhood physical abuse and combat-related posttraumatic stress disorder in Vietnam veterans.

It is suggested that patients seeking treatment for combat-related PTSD have higher rates of childhood physical abuse than combat veterans without PTSD.

Psychophysiologic assessment of women with posttraumatic stress disorder resulting from childhood sexual abuse.

Heart rate, skin conductance, and left lateral frontalis and corrugator facial electromyogram responses were measured during script-driven imagery of personal childhood sexual abuse and other life experiences among women with and without posttraumatic stress disorder (PTSD) resulting from CSA.

Childhood adversity and adult psychiatric disorder in the US National Comorbidity Survey.

The existence of strong clustering among childhood adversities and lifetime co-morbidity among adult disorders means that caution is needed in interpreting the results of previous single-adversity single-disorder studies as documenting unique effects of specific Childhood adversities on specific adult disorders.