Association between biomarkers of endothelial injury and hypocoagulability in patients with severe sepsis: a prospective study

@inproceedings{Ostrowski2015AssociationBB,
  title={Association between biomarkers of endothelial injury and hypocoagulability in patients with severe sepsis: a prospective study},
  author={Sisse Rye Ostrowski and Nicolai Rosenkrantz Segelcke Haase and Rasmus Beier M{\"u}ller and Morten Hylander M\oller and Frank Christian Pott and Anders Perner and P{\"a}r Ingemar Johansson},
  booktitle={Critical care},
  year={2015}
}
INTRODUCTION Patients with severe sepsis often present with concurrent coagulopathy, microcirculatory failure and evidence of vascular endothelial activation and damage. Given the critical role of the endothelium in balancing hemostasis, we investigated single-point associations between whole blood coagulopathy by thrombelastography (TEG) and plasma/serum markers of endothelial activation and damage in patients with severe sepsis. METHODS A post-hoc multicenter prospective observational study… CONTINUE READING
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