Association between autoantibodies to the Arginine variant of the Zinc transporter 8 (ZnT8) and stimulated C-peptide levels in Danish children and adolescents with newly diagnosed type 1 diabetes.

@article{Andersen2012AssociationBA,
  title={Association between autoantibodies to the Arginine variant of the Zinc transporter 8 (ZnT8) and stimulated C-peptide levels in Danish children and adolescents with newly diagnosed type 1 diabetes.},
  author={Marie Louise Max Andersen and Fariba Vaziri-Sani and Ahmed J. Delli and Sven P{\"o}rksen and Emma Jacobssen and Jane Froelund Thomsen and Jannet Svensson and Jacob Steen Petersen and Lars Hansen and {\AA}ke Lernmark and Henrik Bindesb\ol Mortensen and Lotte Br\ondum Nielsen},
  journal={Pediatric diabetes},
  year={2012},
  volume={13 6},
  pages={
          454-62
        }
}
BACKGROUND The zinc transporter 8 (ZnT8) was recently identified as a common autoantigen in type 1 diabetes (T1D) and inclusion of ZnT8 autoantibodies (ZnT8Ab) was found to increase the diagnostic specificity of T1D. OBJECTIVES The main aims were to determine whether ZnT8Ab vary during follow-up 1 year after diagnosis, and to relate the reactivity of three types of ZnT8Ab to the residual stimulated C-peptide levels during the first year after diagnosis. SUBJECTS A total of 129 newly… CONTINUE READING

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SLC30A8 (ZnT8) polymorphism is associated with young age at type 1 diabetes

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