Association between atopic dermatitis and insulin-dependent diabetes mellitus: a case-control study

@article{Olesen2001AssociationBA,
  title={Association between atopic dermatitis and insulin-dependent diabetes mellitus: a case-control study},
  author={Anne Braae Olesen and Svend Juul and Niels Holtum Birkeb{\ae}k and Kristian thestrup-pedersen},
  journal={The Lancet},
  year={2001},
  volume={357},
  pages={1749-1752}
}
BACKGROUND Up to two-thirds of children with atopic dermatitis have IgE-mediated allergic reactions and a Th2 immune reactivity pattern with low production of interferon gamma and high production of interleukin 4 after allergen stimulation of T lymphocytes. Insulin-dependent diabetes mellitus (IDDM) seems to be associated with a Th1 immune reactivity pattern. We therefore postulated that these diseases may be inversely associated. METHODS We designed a case-control study including 920… CONTINUE READING

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