Association between apolipoprotein E epsilon4 and the rate of cognitive decline in community-dwelling elderly individuals with and without dementia.

@article{Jonker1998AssociationBA,
  title={Association between apolipoprotein E epsilon4 and the rate of cognitive decline in community-dwelling elderly individuals with and without dementia.},
  author={Cees Jonker and Ben A. Schmand and Jaap Lindeboom and Louis M. Havekes and Lenore J. Launer},
  journal={Archives of neurology},
  year={1998},
  volume={55 8},
  pages={1065-9}
}
OBJECTIVE To determine whether the apolipoprotein E epsilon4 allele (apoE epsilon4) is associated with cognitive decline in individuals with and without dementia, we conducted a 4-year longitudinal study of subjects with a range of cognitive function. SETTING At baseline, respondents (n=511) were randomly selected according to age and Mini-Mental State Examination score from a community-based study of dementia among noninstitutionalized persons aged 65 to 84 years. Respondents were examined… CONTINUE READING

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