Association between angiotensin-converting enzyme insertion/deletion polymorphism and migraine: a meta-analysis

@article{Wan2016AssociationBA,
  title={Association between angiotensin-converting enzyme insertion/deletion polymorphism and migraine: a meta-analysis},
  author={Dongjun Wan and Chunyu Wang and Xiao-fei Zhang and Wenjing Tang and Min Chen and Zhao Dong and Shengyuan Yu},
  journal={International Journal of Neuroscience},
  year={2016},
  volume={126},
  pages={393 - 399}
}
Background: Many studies investigated the association between angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism and migraine, with controversial results. Thus, we performed a meta-analysis to better evaluate the correlation of this polymorphism and migraine. Methods: We retrieved studies published up to September 2014 about the ACE gene polymorphism and migraine from electronic database. Pooled odds ratios (ORs) with 95% confidence interval (CI) were calculated to… 

Angiotensin-converting enzyme gene polymorphisms and nonarteritic anterior ischemic optic neuropathy risk

TLDR
ACE rs4309, rs4646994 polymorphisms may be associated with the occurrence of NAION in Chinese Han population and A-C-A, T-G-G haplotypes are also the risk factors for NAION.

Genetic variants in migraine: a field synopsis and systematic re-analysis of meta-analyses

TLDR
Several noteworthy variants for migraine susceptibility are identified in this field synopsis and re-analysis study to evaluate the noteworthiness using a Bayesian approach in hope of finding true associations.

Plasma ACE activity after aerobic exercise training is related to sleep in migraine patients: A secondary, per protocol analysis

TLDR
It is suggested that aerobic exercise training increases plasma ACE activity with possible implication on sleep regulation in migraine patients, and among patients, the migraine exercise group showed greater numeric reduction in the number of sleep deprivation-triggered attacks compared to migraine waitlist group and lower insomnia scores.

MiR-30a relieves migraine by degrading CALCA.

  • Y. ZhaiY.-Y. Zhu
  • Biology
    European review for medical and pharmacological sciences
  • 2018
TLDR
expression levels of miR-30a are significantly decreased in migraine patients and can relieve migraine through the degradation of CALCA.

activity after aerobic exercise training is related to sleep in migraine patients: A secondary, protocol

TLDR
The reasons for the creation of the Migraine Tree, its design and underlying principles, and future collaborations for translation in other languages are summarized andArt contests are useful tools for disease awareness.

Migraine (Shaqeeqa) and its management in Unani medicine

TLDR
Migraine is a disease majorly affecting one side of the head and characterized by recurrent attacks of pulsating headache, mostly associated with nausea, vomiting, photophobia and phonophobia, with or without an aura.

Migraine (Shaqeeqa) and its management in Unani medicine

TLDR
Migraine is a disease majorly affecting one side of the head and characterized by recurrent attacks of pulsating headache, mostly associated with nausea, vomiting, photophobia and phonophobia, with or without an aura.

References

SHOWING 1-10 OF 44 REFERENCES

Angiotensin-converting enzyme gene insertion/deletion polymorphism in migraine patients

TLDR
ACE genotype in the experience did not predict the clinical response to lisinopril or candesartan used as migraine prophylactics and there was no association between ACE genotype or allele frequency and migraine.

Association between migraine and ACE gene (insertion/deletion) polymorphism: the BioBIM study.

TLDR
Although theACE I/D polymorphism is not a direct risk factor for migraine, the ACE I/I genotype may influence the clinical feature of this disease being associated with reduced use of prophylactic agents in patients with migraine with aura and in those with chronic migraine.

Homozygous deletion genotype of angiotensin converting enzyme confers protection against migraine in man.

TLDR
The findings indicate that ACE-DD may have a slight protective effect against migraine in male patients, and there was no existence of a difference among the frequency and duration of headache in each subgroup of migraine patients stratified by ACE genotype.

Endothelial Nitric Oxide Synthase and Angiotensin Converting Enzyme Gene Polymorphisms in Migraine Patients.

TLDR
The findings support the relationship between migraine and the ACE I/D gene polymorphism, however, no association was found between migraines and the eNOS 4 a/b gene polymorphisms.

ACE D/I polymorphism, migraine, and cardiovascular disease in women

TLDR
Data from this large cohort of women do not suggest an association of the ACE deletion/insertion (D/I) polymorphism with migraine, migraine aura status, or cardiovascular disease (CVD).

Migraine and coronary artery disease: an open study on the genetic polymorphism of the 5, 10 methylenetetrahydrofolate (MTHFR) and angiotensin I-converting enzyme (ACE) genes.

TLDR
Evidence is given of a strong relationship between migraine and major vascular diseases and an important role of ACE and MTHFR system in the pathogenetic model of migraine for its capability to interfere with the endothelial regulation tone is hypothesized.

The role of angiotensin-converting enzyme gene in migraine patients.

TLDR
The results of this study confirm the association between migraine and ACE I/D genetic polymorphism and allow us to hypothesize an important role of A CE system in the genetic model of migraine due to its capability to interfere with th e endothelial regulatory tone.

Angiotensin I‐Converting Enzyme Gene (I/D) Polymorphism in Patients With Migraine

TLDR
The results of this study suggest that the angiotensin‐converting enzyme D/D genotype may be a genetic risk factor for migraine with aura in Turkish patients.