Association between anal function and therapeutic effect after preoperative chemoradiotherapy followed by intersphincteric resection.

@article{Nishizawa2012AssociationBA,
  title={Association between anal function and therapeutic effect after preoperative chemoradiotherapy followed by intersphincteric resection.},
  author={Yuji Nishizawa and Norio Sait{\^o} and Satoshi Fujii and Masaaki Ito and Masanori Sugito and Akihiro Kobayashi and Yusuke Nishizawa},
  journal={Digestive surgery},
  year={2012},
  volume={29 5},
  pages={439-45}
}
BACKGROUND/AIMS Preoperative chemoradiotherapy (CRT) for rectal cancer improves local control, but can also induce severe anal dysfunction after surgery. The goal of the study was to assess the relationship of the therapeutic effect of CRT with anal function and prognosis after intersphincteric resection (ISR). METHODS The subjects were 37 patients with lower rectal cancer who underwent ISR with preoperative CRT. The rectal cancer regression grade (RCRG) was quantified based on histologic… CONTINUE READING

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