Association between albuminuria, kidney function, and inflammatory biomarker profile in CKD in CRIC.

@article{Gupta2012AssociationBA,
  title={Association between albuminuria, kidney function, and inflammatory biomarker profile in CKD in CRIC.},
  author={Jayanta Gupta and Nandita Mitra and Peter A. Kanetsky and Joe M Devaney and Maria R. Wing and Muredach Reilly and Vallabh O. Shah and Vaidyanathapura S Balakrishnan and Nicolas J. Guzman and Matthias Girndt and Brian G Periera and Harold I. Feldman and John Walter Kusek and Marshall M. Joffe and Dominic S. C. Raj},
  journal={Clinical journal of the American Society of Nephrology : CJASN},
  year={2012},
  volume={7 12},
  pages={1938-46}
}
BACKGROUND AND OBJECTIVES Increased risk of mortality in patients with CKD has been attributed to inflammation. However, the association between kidney function, albuminuria, and biomarkers of inflammation has not been examined in a large cohort of CKD patients. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS This study measured the plasma levels of IL-1β, IL-1 receptor antagonist (IL-1RA), IL-6, TNF-α, TGF-β, high-sensitivity C-reactive protein (hs-CRP), fibrinogen, and serum albumin in 3939… CONTINUE READING

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