Association between airway caliber changes with lung inflation and emphysema assessed by volumetric CT scan in subjects with COPD.

@article{Diaz2012AssociationBA,
  title={Association between airway caliber changes with lung inflation and emphysema assessed by volumetric CT scan in subjects with COPD.},
  author={Alejandro Diaz and Carolyn E. Come and James C. Ross and Ra{\'u}l San Jos{\'e} Est{\'e}par and Meilan K. Han and Stephen H Loring and Edwin K. Silverman and George R. Washko},
  journal={Chest},
  year={2012},
  volume={141 3},
  pages={736-744}
}
BACKGROUND An increase in airway caliber (airway distensibility) with lung inflation is attenuated in COPD. Furthermore, some subjects have a decrease in airway caliber with lung inflation. We aimed to test the hypothesis that airway caliber increases are lower in subjects with emphysema-predominant (EP) compared with airway-predominant (AP) CT scan subtypes. Additionally, we compared clinical and CT scan features of subjects with (airway constrictors) and without a decrease in airway caliber… CONTINUE READING